View our

CLINICAL TRIALS

Clinical Trials for

Acute Lymphoblastic Leukemia

 

 

 

 

 

 

 

  • AALL1131 – A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum

 

 

 

 

 

  • ACCL0934 – A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

 

  • AALL05B1 – A Children’s Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

Clinical Trials for

Acute Myeloid Leukemia

 

Clinical Trials for

Brian Tumors

Clinical Trials for

Chronic Myeloid Leukemia

Clinical Trials for

Ewing Sarcoma

Clinical Trials for

Hepatoblastoma

  • AHEP0731 – Treatment of Children with All Stages of Hepatoblastoma with Temsirolimus (IND#122782, NSC#683864) Added to High Risk Stratum Treatment

Clinical Trials for

Juvenile Myelomonocytic Leukemia

  • ASCT1221 – A Randomized Phase II Study Comparing Two Different Conditioning Regimens Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Children with Juvenile Myelomonocytic Leukemia (JMML)
  • NYMC 504 – Allogeneic Stem Cell Transplantation Followed by Targeted Immune Therapy in Average Risk Myelogenous Leukemia/Myelodysplastic Syndrome/Juvenile Myelomonocytic Leukemia (AML/MDS/JMML)

Clinical Trials for

Kidney Tumors

  • NYMC 165 – A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving “ICE” Chemotherapy (IND 122872)
  • AREN03B2 – Renal Tumors Biology Studies

Clinical Trials for

Neuroblastoma

  • ANBL0032 – Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue.
  • ANBL1221 – A Phase II Randomized Trial of Irinotecan/Temozolomide with Temsirolimus (NSC# 683864, IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408, IND#4308) in Children with Refractory, Relapsed or Progressive Neuroblastoma
  • ANBL1232 – Utilizing Response & Biology-Based Risk Factors to Guide Therapy in Patients with Non-High Risk Neuroblastoma
  • ANBL00B1 – Neuroblastoma biology studies
  • NYMC 165 – A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving “ICE” Chemotherapy (IND 122872)

Clinical Trials for

Non-Hodgkins Lymphoma (Burkitt, Large Cell, Lymphoblastic, Anaplastic)

Clinical Trials for

Sickle Cell Disease

  • NYMC 526 – Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease – Lead Institution (HaploSCD)
  • NYMC 556 – Allogeneic Stem Cell Transplant to Induce Mixed Donor Chimerism in Patients with Sickle Cell Disease and Thalassemia
  • NYMC-571 The Safety and Efficacy of Prophylactic Defibrotide Administration in Children, Adolescents, and Young Adults with Sickle Cell Disease Following Myeloablative Conditioning (MAC) and Haploidentical Stem Cell Transplantation Utilizing CD34 Enrichment and T-Cell (CD3) Addback (IND 127812)
  • NYMC-192 A phase II study to determine the safety of defibrotide in Sickle Cell Disease-related acute chest syndrome  (IND 127812)

Clinical Trials for

Solid Tumors

  • A Study to Evaluate 5 μg/kg Tbo-filgrastim in Infants, Children and Adolescents With Solid Tumors Without Bone Marrow Involvement
  • D9902 – A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol
  • NYMC 165 – A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving “ICE” Chemotherapy (IND 122872)
  • ARST1321 – Pazopanib Neoadjuvant Trial In Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613)
  • A0ST06B1 – Osteosarcoma Biology Studies
  • AEWS07B1 – Ewing Sarcoma Biology Studies
  • AEWS1031 – A phase III randomized trial of adding vincristine – topotecan- cyclophosphamide to standard chemotherapy in initial treatment of non-metastatic Ewing sarcoma
  • AEWS1221 -Randomized phase II trial evaluating the addition of the IGF – 1R monoclonal antibody Ganitumab to multiagent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma

Clinical Trials for

Thalassemia

Clinical Trials for

Wellness and Survivorship

  • NYMC 168 – Cancer and Blood Marrow Transplantation Wellness and Survivorship Research

Clinical Trials for

Wilms Tumor

  • CCG4914L – National Wilms Tumor Late Effects Study

Clinical Trials for

Other